Vitamin B12, also known as cobalamin, is soluble in water and it is found in several common foods. Vitamin B12 is necessary for the synthesis of DNA and a deficiency causes anemia and neurological dysfunction. A symptom of B12 deficiency anemia is fatigue, which can be alleviated with vitiamline supplements. However, the consumption of B12 supplements when there are no deficiencies, has no effect on fatigue. If you suspect that you have a B12 deficiency, you can consult your doctor and do an analysis.
Sources of vitamin B12
Vitamin B12 is usually present in meats and dairy products, as well as in fortified breakfast cereals and vegetarian products that mimic meat. It is a water soluble vitamin, but unlike other similar vitamins that are eliminated through the urine when consumed in excess, cobalamin is stored in the liver. The recommended daily intake of vitamin B12 increases with age, in pregnant women and in breastfeeding women, but it is usually between 2, 4 to 2, 8 micrograms per day.
Vitamin B12 deficiency
Vitamin B12 interacts with tetrahydrofolate to synthesize deoxythymidine triphosphate, which is one of the four DNA nucleotides. Therefore, B12 deficiency prevents DNA synthesis. This causes problems in the regeneration of red blood cells (RBC), since these cells normally synthesize DNA at high rates. Problems in the production of GR cause anemia, which is characterized by fatigue, weakness and constipation. The most severe deficiencies of B12 cause neurological dysfunction, which is characterized by tingling in the hands and feet, memory problems and depression. However, as vitamin B12 is stored in the liver, deficiencies can take years or decades to develop.
Causes of B12 deficiency
B12 deficiency is usually the result of poor intestinal absorption or inadequate intake. malabsorption can be caused by diseases that affect the functioning of the stomach and small intestine, including atrophic gastritis, pernicious anemia (an autoimmune disorder), celiac disease, and Chron's disease. Surgeries in the small intestine can also affect your ability to absorb B12. Inadequate intake can occur in vegetarians and vegans who do not consume fortified foods or take B12 supplements.
Fatigue can have many causes, including sleeping problems, heart and lung diseases, endocrine disorders, cancer, and infections. Although B12 deficiency causes anemia related to fatigue, there is no evidence that B12 supplements are beneficial for fatigue in the absence of deficiency.However, if you have a deficiency, the consumption of vitamin B12 supplements could solve the problem of fatigue. The only way to determine if you have a deficiency of vitamin B12 or not, is to consult the doctor and perform an analysis.
If you think you have a deficiency, you can consult the doctor and perform an analysis. The B12 analyzes first determine if there is a deficiency and then the cause of it. In general, treatment involves taking supplements. If you do a B12 test and there are no deficiencies, but you still feel fatigued, your doctor can perform other tests to find the cause of the problem.